Clinical Articles

Endometriosis affects one in seven women and is more common in certain groups, affecting 50% of women with chronic pelvic pain, 40% of women with subfertility and 25% of transgender men. Symptoms include pelvic pain, dysmenorrhoea, dyschezia, dyspareunia, fatigue and subfertility. Read More...

Endometriosis is a complex and often debilitating condition affecting millions worldwide. Characterised by the growth of endometrial-like tissue outside the uterus, it can lead to chronic pelvic pain, dysmenorrhoea, and infertility. Hormonal therapies are a cornerstone of endometriosis management, aiming to reduce oestrogen levels and alleviate symptoms. There remains an important clinical need for safe, highly effective, convenient medical treatments that can be used long term for endometriosis related pain, which may reduce the need for opioids and repeated surgery. Read More...

Several studies have recognised the menopausal symptoms such as joint pains, hot flushes and low morale impact significantly on the lives of women. Doctors need to appreciate the needs of individual women transitioning to menopause and perimenopause and assist in education and symptom management. Read More...

Breast density (also called mammographic breast density) is a term used to describe how relative amounts of breast tissue appear on a mammogram. Read More...

Osteoarthritis (OA) is a major cause of chronic knee pain and disability with a reported prevalence of 25-30% of the population over 60 years of age. While traditionally thought of as a purely degenerative disease related to “wear and tear”, the pathophysiology of OA involves a complex interplay of mechanical, biological, and molecular factors leading to inflammation, pain, and structural degeneration. Read More...

Rapid weight loss in older people is defined as the involuntary decline in total body weight by >5% over a six to 12-month period. This magnitude of weight loss has been suggested by some to be an indicator of health status, and unintentional weight loss occurs in up to one in four community-dwelling frail older adults. Read More...

Obesity is a major public health problem that is associated with serious comorbidities, including diabetes, dyslipidaemia, cancer and cardiovascular disease (CVD), with premature mortality. Its prevalence has been increasing over the past few decades and is a modern-day pandemic since 2012. Read More...

The old adage that prevention is better than cure holds strong for cardiovascular disease (CVD). Accounting for 25% of all Australian deaths, CVD costs the Australian health system $12.7 billion annually, placing an enormous burden on individuals, their family and the economy. Read More...