Acute respiratory infections in children with neurodisability
Pneumonia, a common cause for acute respiratory infection, is one of the most common causes of hospital admissions in children. Read More...
Clinical Articles
Real-time intraoperative digital pathology for surgical oncology
Accurate decision-making during surgical resection of various human cancers is reliant on good communication between surgeon and pathologist. The frozen section is essentially unchanged since described by pathologist Dr Louis B. Wilson in 1905 at the request of surgeon Dr William Mayo, one of the founders of the Mayo Clinic. Read More...
De-escalation of surgical management of the axilla in breast cancer
Management of the draining axillary lymph nodes in breast cancer has thankfully come a long way since the Halsted radical mastectomy. While it is still vital to stage the axilla, as it remains a critical component of prognosis, there is an ongoing trend for surgical de-escalation. Read More...
Mental disturbance in the perinatal period
There is growing awareness of perinatal depression, but anxiety disorders are more common and often overlooked, affecting up to 30% of pregnant women. There is less awareness still of perinatal obsessive compulsive disorder (OCD), yet up to 40 out of 100 anxious and/or depressed women also report obsessional, intrusive thoughts of harming the baby. Read More...
The overactive bladder
Overactive bladder (OAB) is defined as “urinary urgency, usually with urinary frequency and nocturia, with or without urgency urinary incontinence (UUI), in the absence of UTI or other obvious pathology”. The prevalence in adults aged over 18 is 10.8% in men and 12.8% in women. UUI is the most bothersome symptom. Read More...
Resistance exercise: frontline defence against sarcopenia
Sarcopenia is the loss of muscle mass in conjunction with reduced strength and/or physical performance. In July 2019, sarcopenia was recognised as a disease with its own International Classification of Disease, ICD-10 code (M62.84). It can also occur secondarily to chronic disease (e.g. cardiovascular disease and diabetes). Read More...
Clinical research – key to improving outcomes in childhood cancer
Survival rates for children with cancer have improved significantly since the 1980s with estimated five-year survival rate rising from 28% to more than 80%. While newer modalities of treatment and better supportive care have contributed to this dramatic survival improvement, the important role played by clinical trials over the years cannot be underestimated. Read More...
Pelvic venous congestion
“If only I had found out earlier” is an all-too-common lament made by patients presenting with often years of “investigated” chronic pelvic pain (CPP) when the diagnosis of Pelvic Congestion Syndrome (PCS) is made. Read More...