Breast cancer update
Updates in endocrine therapy for metastatic hormone receptor positive advanced breast cancer management and mechanisms of overcoming endocrine resistance. Read More...
Clinical Articles
Iron Infusions and Hypophosphataemia
Iron deficiency anaemia is a common condition that can have a significant impact on a patient’s quality of life. The incidence of iron deficiency anaemia in Australia is estimated to be 12% in non-pregnant and up to 15% of pregnant females.1 Iron deficiency without anaemia may be up to three times more common but is often undiagnosed. Read More...
Extracellular matrix: the scaffold of life
Muscle fibres are the motors that power our movements, allowing us to walk, run, eat or hug a loved one. But the extracellular matrix (ECM), a dynamic and complex network of proteins and molecules within which our fibres are housed, is now known to play an essential role in muscle function, growth, injury recovery and ageing. Read More...
CT scan radiation risk
CT is one of the most transformative advances in medicine in the past 100 years. It is estimated to have a substantial impact on the speed of diagnosis in 50% of cases and, in a high proportion, the result is decisive in outcome. Approximately 15 per 1000 people undergo a CT scan annually in Australia. Read More...
Advances in resection of impalpable breast lesions
Non-palpable breast lesions are not easy to resect without prior localisation. With the increased uptake of breast screening, there are more impalpable lesions detected that requires surgical excision – indeterminate and biopsy proven malignant lesions. Read More...
Transcatheter mitral valve repair (TMVr) in severe mitral regurgitation
Mitral regurgitation (MR) affects 2% of the population and can be grouped into those with primary (degenerative) or secondary (functional) mitral regurgitation. The best way I describe this to patients is that there is either a problem with the door and hinges, or the frame of the door. Read More...
Common sleep disturbances in children
Snoring is very common, affecting about around 10-30% of young children. When habitual (three or more nights per week) or with observed apnoea, this needs further evaluation for OSA. Read More...
Precision medicine in paediatric ENT disorders
Precision medicine is an emerging approach to disease treatment and prevention that considers individual gene variability, environment and lifestyle. In contrast to a one-size-fits-all approach, improved outcomes can be achieved with individually targeted health-care advice. This is especially powerful in oncology, with treatments based on the individual’s tumour genetics. Read More...