Semaglutide approved for diabetic chronic kidney disease

By Dr Prue Gregory, Advanced Trainee in Renal Medicine, and Dr Aron Chakera, Nephrologist, North Metropolitan Health Service

Diabetic kidney disease is now the leading cause of progressive chronic kidney disease (CKD) and kidney failure in Australia and other developed countries.

CKD is itself a major risk factor for cardiovascular disease and the cardiovascular-kidney-metabolic (CKM) syndrome is now being recognised by authorities to highlight the link between heart disease, kidney disease, diabetes and obesity as a driver of poor health outcomes.

Recent randomised-trial evidence has expanded the role of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) from...

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