The liver fibrosis 4 index simplified

By Professor Leon Adams, Hepatologist and Dr Matthew Garas

Metabolic dysfunction-associated fatty liver disease (MAFLD) is now the most common liver condition in Australia and globally.

Previously termed non-alcoholic fatty liver disease (NAFLD), MAFLD is defined by hepatic steatosis in the presence of metabolic risk factors such as type 2 diabetes, overweight or obesity, dyslipidemia and hypertension.

The shift in nomenclature places greater emphasis on the underlying pathogenesis and recognises its potential to co-exist with additional liver risk factors such as alcohol excess....

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